Carbon Disulfide → 2-Methyl-3-hydroxy-4-mercaptomethyl-5-hydroxymethyl-6-vinylpyridine

Reaction equation

[CH3:1][C:2]1[C:7]([OH:8])=[C:6]([CH2:9]O)[C:5]([CH2:11][OH:12])=[C:4]([CH:13]=[CH2:14])[N:3]=1.[OH-].[Na+].C(=S)=[S:18]>>[CH3:1][C:2]1[C:7]([OH:8])=[C:6]([CH2:9][SH:18])[C:5]([CH2:11][OH:12])=[C:4]([CH:13]=[CH2:14])[N:3]=1

Participants

Reactant 3

HCID 6348Carbon Disulfide

HCID 14798Sodium Hydroxide

HCID 202640222-Methyl-3-hydroxy-4,5-di(hydroxymethyl)-6-vinylpyridine

Product 1

HCID 202639312-Methyl-3-hydroxy-4-mercaptomethyl-5-hydroxymethyl-6-vinylpyridine

Procedure

Treatment of the product of Step D with sodium hydroxide and carbon disulfide by the procedure described in Example 1, Step C, yields 2-methyl-3-hydroxy-4-mercaptomethyl-5-hydroxymethyl-6-vinylpyridine.

Sources & evidence

ORD record: ord-58d2e1c6757844d0a473cfcc3573cc11
Source dataset: uspto-grants-1979_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04144342

Reaction notes

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