Etidronic Acid → ZINC etidronate

HRID 615829

Reaction equation

HRID 615829 reaction equation
[CH3:1][C:2]([P:8]([OH:11])([OH:10])=[O:9])([P:4]([OH:7])([OH:6])=[O:5])[OH:3].[O-2].[Zn+2:13]>>[Zn:13].[CH3:1][C:2]([P:8]([OH:11])([OH:10])=[O:9])([P:4]([OH:7])([OH:6])=[O:5])[OH:3]

Participants

3

Reactant 2

HCID 3305Etidronic AcidHCID 3007857Zinc Oxide

Product 1

HCID 86739934ZINC etidronate

Procedure

682 grams of a 60 percent aqueous solution of etidronic acid was added slowly to a stirred slurry of 400 grams zinc oxide in 1.45 Kg distilled water. A dense white amorphous precipitate was produced and settled when agitation had stopped to leave a clear liquor. The reaction was exothermic. The mixture was filtered and the precipitate was washed with distilled water and dried at 110° C. 863 grams of a zinc etidronate having a zinc to etidronate molar ratio of 2.4:1 was obtained.

Workup

  1. distillationdistilled water
  2. customA dense white amorphous precipitate was produced
  3. customto leave a clear liquor
  4. filtrationThe mixture was filtered
  5. washthe precipitate was washed with distilled water
  6. customdried at 110° C

Sources & evidence

ORD record
ord-a2e0aea7a700459cbd8fee4c7cdc049f
Source dataset
uspto-grants-1985_02
Patent number
US04501615

Linked notes

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