Lactic Acid → 2-Acetoxypropionic Acid

HRID 616058

Reaction equation

HRID 616058 reaction equation
[C:1]([O:4][CH:5]([CH3:8])[CH:6]=[O:7])(=[O:3])[CH3:2].C(OCCC(O)=O)(=[O:11])C.C(OC(=O)C)(=O)C.C(O)(=O)C(C)O>>[C:1]([O:4][CH:5]([CH3:8])[C:6]([OH:11])=[O:7])(=[O:3])[CH3:2]

Participants

5

Reactant 4

HCID 612Lactic AcidHCID 7918Acetic AnhydrideHCID 907282-(Acetyloxy)propanalHCID 126471513-(Acetyloxy)propanoic acid

Product 1

HCID 790412-Acetoxypropionic Acid

Procedure

α-Acetoxypropionaldehyde and β-acetoxypropionic acid were identified by elemental analysis, molecular weight, and nuclear magnetic resonance studies. An authentic sample of α-acetoxypropionic acid was prepared by the addition of acetic anhydride to lactic acid [A. Golomb and P. D. Ritchie, J CHEM SOC, 838 (1962)]. The corresponding aldehyde could not be prepared by an independent method.

Sources & evidence

ORD record
ord-3a9392ef53f34287a499c1a8757be45c
Source dataset
uspto-grants-1978_02
Patent number
US04072709

Linked notes

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