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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61713Generated: October 23, 2026

2-Bromopyrimidine → 6,6-Dimethyl-11-oxo-8-(pyrimidin-2-yloxy)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

https://huagongshe.com/en/reaction/61713

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromopyrimidineHCID 78345—
Reactant8-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrileHCID 66833861—
Product6,6-Dimethyl-11-oxo-8-(pyrimidin-2-yloxy)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrileHCID 66834103—

Reaction Steps

Under the same conditions as the method for synthesizing Compound A7-17, the title compound was prepared from Compound A6 and 2-bromopyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440922B2
Source datasetuspto-grants-2016_09
ORD IDord-1516b8de47314b2f849f64e9e744b18b
Source noteuspto-grants-2016_09