3-Chloro-4-methoxybenzylamine → Thieno(2,3-d)pyrimidine

Reaction equation

ClC1C=C(C=CC=1OC)CN.Cl[C:13]1[N:14]=[C:15](Cl)[C:16]2[CH:21]=[C:20]([N+]([O-])=O)[S:19][C:17]=2[N:18]=1>>[N:18]1[C:17]2[S:19][CH:20]=[CH:21][C:16]=2[CH:15]=[N:14][CH:13]=1

Participants

Reactant 2

HCID 7380383-Chloro-4-methoxybenzylamine

HCID 18460040HCID 18460040, compound

Product 1

HCID 12225304Thieno(2,3-d)pyrimidine

Procedure

Following the procedure of Example 1, the reaction of 3-chloro-4-methoxybenzylamine with 2,4-dichloro-6-nitro-thieno-[2,3-d]-pyrimidine yields 2-chloro-6-nitro-4-93-chloro-4-methoxybenzylamino)-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record: ord-f5d9a37b689b430f9ac0b7450484b97d
Source dataset: uspto-grants-1999_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05948911

Reaction notes

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