Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61749Generated: October 24, 2026

Captamine Hydrochloride → 8-(2-Dimethylamino-ethylsulfanyl)-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

https://huagongshe.com/en/reaction/61749

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCaptamine HydrochlorideHCID 25798—
ReactantTrifluoro-methanesulfonic acid 3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl esterHCID 86663817—
Product8-(2-Dimethylamino-ethylsulfanyl)-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrileHCID 66834684—

Reaction Steps

Under the same conditions as the method for synthesizing Compound B2-17, the title compound was prepared from Compound B1 and 2-dimethylaminoethanethiol hydrochloric acid salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440922B2
Source datasetuspto-grants-2016_09
ORD IDord-afe98b2d85414411806e8b7470c4e914
Source noteuspto-grants-2016_09