Water → 3,6-Dimethyl-2,4-dinitroaniline
Reaction equation
[CH3:1][C:2]1[C:3]([N+:16]([O-:18])=[O:17])=[C:4]([NH:12]C(=O)C)[C:5]([CH3:11])=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9].S(=O)(=O)(O)O.O>C(O)C>[CH3:1][C:2]1[C:3]([N+:16]([O-:18])=[O:17])=[C:4]([NH2:12])[C:5]([CH3:11])=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of N-(3,6-dimethyl-2.4-dinitro-phenyl)-acetamide (14.4 g, from above), concentrated sulfuric acid (15 mL), water (30 mL) and ethanol (150 mL) was heated at reflux for 24 hr. The precipitated product was filtered, washed with little ethanol and dried to afford 3,6-dimethyl-2.4-dinitro-phenylamine (10.3 g).
Workup
- temperaturewas heated
- temperatureat reflux for 24 hr
- filtrationThe precipitated product was filtered
- washwashed with little ethanol
- customdried
Sources & evidence
- ORD record
- ord-432111e3e3984d4c898f8dbe81b5a471
- Source dataset
- uspto-grants-1999_09
- Patent number
- US05952362
Reaction notes
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