HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 4-(2-Propenyl)-1-methyl-5-pyrazole sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-(1-Hydroxypropyl)-1-methyl-5-tert-butylpyrazolesulfonamide | HCID 21243739 | — |
| Product | 4-(2-Propenyl)-1-methyl-5-pyrazole sulfonamide | HCID 21243741 | — |
Reaction Steps
The alcohol (3.0 g) from Example 3 was stirred in 25 ml of trifluoroacetic acid at 68° C. for 30 minutes. The solution was allowed to cool to room temperature, and the volatile components were removed in vacuo to afford 510 mg of the desired sulfonamide, m.p. 157°-161° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04822403 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-87a32f0f385641ae8075ac023a4c575f |
| Source note | uspto-grants-1989_04 |