Acetic Acid → Tetrafluorophthalic anhydride

Reaction equation

C(N1[C:8](=[O:9])[C:7]2=[C:10]([F:17])[C:11]([F:16])=[C:12]([F:15])[C:13]([F:14])=[C:6]2[C:5]1=[O:18])(C)C.S(=O)(=O)(O)[OH:20].C(O)(=O)C>O>[F:17][C:10]1[C:11]([F:16])=[C:12]([F:15])[C:13]([F:14])=[C:6]2[C:5](=[O:18])[O:9][C:8](=[O:20])[C:7]=12

Participants

Procedure

In a 500 ml three neck distillation flask were placed 47 g (0.18 mol) of N-isopropyl-tetrafluorophthalimide, 71 ml of concentrated sulfuric acid, 43 ml of acetic acid, and 13 ml of water, and the mixture was reacted for 5 hours at 140° to 150° C. with stirring. After cooling, the reaction mixture was extracted three times with 200 ml of toluene, and the toluene layers thus formed were collected and concentrated by distillation under a reduced pressure to provide 26.3 g (yield 66.4%) of tetrafluorophthalic anhydride as white crystals.