Nitric Acid → 5,6-Dinitro-1H-indazole

HRID 629688

Reaction equation

HRID 629688 reaction equation
[N+:1]([C:4]1[CH:12]=[C:11]2[C:7]([CH:8]=[N:9][NH:10]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[N+:13]([O-])([OH:15])=[O:14]>C(O)(=O)C>[N+:13]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][C:4]=1[N+:1]([O-:3])=[O:2])[NH:10][N:9]=[CH:8]2)([O-:15])=[O:14]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 242396-Nitroindazole

Product 1

HCID 960635,6-Dinitro-1H-indazoleYield 28.6%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

By referring to the Step 1 of Example 7, 6-nitroindazole (5 g, 30.7 mmol), 35 mL of acetic acid, concentrated HNO3 (3.6 mL, 181.6 mmol), were used to obtain a product (1.8 g, 28.6%).

Sources & evidence

ORD record
ord-efd5e04f12e845a8a3674bc03824a8f7
Source dataset
uspto-grants-2016_04
Patent number
US09315513B2

Linked notes

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