2,4-Dichloroaniline → 6-(2,4-Dichloro-phenylamino)-5-methyl-pyridine-2-carboxylic acid methyl ester

HRID 631954

Reaction equation

HRID 631954 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([CH3:11])=[C:7](Cl)[N:6]=1)=[O:4].[Cl:13][C:14]1[CH:20]=[C:19]([Cl:21])[CH:18]=[CH:17][C:15]=1[NH2:16]>>[CH3:1][O:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([CH3:11])=[C:7]([NH:16][C:15]2[CH:17]=[CH:18][C:19]([Cl:21])=[CH:20][C:14]=2[Cl:13])[N:6]=1)=[O:4]

Participants

3

Reactant 2

HCID 111232,4-DichloroanilineHCID 18324417Methyl 6-chloro-5-methylpyridine-2-carboxylate

Product 1

HCID 710872626-(2,4-Dichloro-phenylamino)-5-methyl-pyridine-2-carboxylic acid methyl ester

Procedure

6-(2,4-Dichloro-phenylamino)-5-methyl-pyridine-2-carboxylic acid methyl ester was synthesized in analogy to Example 5 b, using 6-chloro-5-methyl-pyridine-2-carboxylic acid methyl ester (CAN 178421-22-2) and 2,4-dichloroaniline as starting materials, MS (EI): m/e 311.3 [M+H]+.

Sources & evidence

ORD record
ord-0c5c8be654d24d68a154d0d3b20df110
Source dataset
uspto-grants-2016_04
Patent number
US09321727B2

Linked notes

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