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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 632384Generated: October 27, 2026

Lithium Hydroxide → 6-((4-Fluorophenyl)(hydroxy)methyl)picolinic acid

https://huagongshe.com/reaction/632384

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantMethyl 6-((4-fluorophenyl)(hydroxy)methyl)picolinateHCID 71087862—
Product6-((4-Fluorophenyl)(hydroxy)methyl)picolinic acidHCID 71087341—

Reaction Steps

In analogy to the procedure described in Example 5 c), methyl 6-((4-fluorophenyl)(hydroxy)methyl)picolinate was saponified with lithium hydroxide to obtain the title compound. MS (EI): m/e=246.1 [M−H]−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-e9f1113113ce4aa38782f3b4c7821a1d
Source noteuspto-grants-2016_04