4-Methoxyphenol → 4-Methoxycyclohexanol (cis,trans)

HRID 633520

Reaction equation

HRID 633520 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1>C(O)(=O)C.[Pt]=O>[CH3:1][O:2][CH:3]1[CH2:8][CH2:7][CH:6]([OH:9])[CH2:5][CH2:4]1

Participants

4

Reactant 1

HCID 90154-Methoxyphenol

Product 1

HCID 1403324-Methoxycyclohexanol (cis,trans)

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 176Acetic AcidSolvent

Conditions

Temperature
50 °C

Procedure

A mixture of 4-methoxyphenol (0.10 g, 0.806 mmol) in acetic acid (10 mL) was added to platinum oxide (0.020 g, 0.088 mmol) in a 50 mL pressure bottle and heated at 50° C. under hydrogen at 30 psi for 1 hour. The solid was removed by filtration, and the filtrate was concentrated to provide the title compound.

Workup

  1. customThe solid was removed by filtration
  2. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-2dc8bd4942754b03ab5ddc5dbd1b51dd
Source dataset
uspto-grants-2016_04
Patent number
US09321764B2

Linked notes

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