1-(4-Methylphenyl)butane-1,3-dione → 5-(4-Methylbenzoyl)-6-methyl-2(1H)-pyridinone

Reaction equation

CC1C=CC([C:8](=O)[CH2:9][C:10](=[O:12])C)=CC=1.[CH3:14][C:15]1[CH:20]=[CH:19][C:18]([C:21](=[O:26])[CH:22]=[C:23]([CH3:25])[NH2:24])=[CH:17][CH:16]=1>>[CH3:14][C:15]1[CH:16]=[CH:17][C:18]([C:21]([C:22]2[CH:8]=[CH:9][C:10](=[O:12])[NH:24][C:23]=2[CH3:25])=[O:26])=[CH:19][CH:20]=1

Participants

Reactant 2

HCID 4326511-(4-Methylphenyl)butane-1,3-dione

HCID 673437903-Amino-1-(4-methylphenyl)but-2-en-1-one

Product 1

HCID 202536325-(4-Methylbenzoyl)-6-methyl-2(1H)-pyridinone

Procedure

first using 1-(4-methylphenyl)-1,3-butanedione to prepare 3-(4-methylphenyl)-1-methyl-3-oxo-1-propenamine.

Sources & evidence

ORD record: ord-46b7ef6e87894393b6ef4f07cf4629c2
Source dataset: uspto-grants-1985_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04560691

Reaction notes

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