Allyl bromide → 4-Allyloxy-3-allylbenzoic acid methyl ester

HRID 638949

Reaction equation

HRID 638949 reaction equation
[CH3:1][O:2][C:3](=[O:14])[C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[C:6]([CH2:11][CH:12]=[CH2:13])[CH:5]=1.[CH2:15](Br)[CH:16]=[CH2:17]>>[CH3:1][O:2][C:3](=[O:14])[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:17][CH:16]=[CH2:15])=[C:6]([CH2:11][CH:12]=[CH2:13])[CH:5]=1

Participants

3

Reactant 2

HCID 7841Allyl bromideHCID 939882Methyl 3-allyl-4-hydroxybenzoate

Product 1

HCID 112417484-Allyloxy-3-allylbenzoic acid methyl esterYield 93%

Procedure

4-Allyloxy-3-allylbenzoic acid methyl ester was prepared by reacting 3-allyl-4-hydroxybenzoic acid methyl ester (Example 49, Step 2) with allyl bromide following Method C in 93% yield. The reaction was conducted at room temperature for 16 h and the resulting product was used without further purification.

Workup

  1. customthe resulting product was used without further purification

Sources & evidence

ORD record
ord-f4c296dd85584bfd8976809853a8fb26
Source dataset
uspto-grants-2010_04
Patent number
US07691843B2

Linked notes

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