HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloromethyl-2-methylpyridinium chloride → 2-Fluoro-4-(6-methyl-pyridin-2-ylmethoxy)-benzoic Acid Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloromethyl-2-methylpyridinium chloride | HCID 76545 | — |
| Reactant | Methyl 2-fluoro-4-hydroxybenzoate | HCID 22463192 | — |
| Product | 2-Fluoro-4-(6-methyl-pyridin-2-ylmethoxy)-benzoic Acid Methyl Ester | HCID 57685108 | — |
Reaction Steps
The title compound is prepared in a manner substantially analogous to Procedure E except KI (1.3 eq.) is also added from 2-Fluoro-4-hydroxy-benzoic acid methyl ester [197507-22-5] and 2-(chloromethyl)-6-methyl-pyridine hydrochloride [CAS 3099-29-4]. MS (ES+) 276.2
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696234B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-776597e184134a44ac87421a55009e6d |
| Source note | uspto-grants-2010_04 |