1-(Bromomethyl)naphthalene → HCID 58900292, compound

HRID 642628

Reaction equation

HRID 642628 reaction equation
C[O:2][C:3]([C:5]1[NH:6][C:7]2[C:12]([CH:13]=1)=[CH:11][CH:10]=[C:9]([C:14]([F:17])([F:16])[F:15])[CH:8]=2)=[O:4].Br[CH2:19][C:20]1[C:29]2[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=2)[CH:23]=[CH:22][CH:21]=1>>[C:20]1([CH2:19][N:6]2[C:7]3[C:12](=[CH:11][CH:10]=[C:9]([C:14]([F:17])([F:16])[F:15])[CH:8]=3)[CH:13]=[C:5]2[C:3]([OH:2])=[O:4])[C:29]2[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=2)[CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 1378441-(Bromomethyl)naphthaleneHCID 7141910methyl 6-(trifluoromethyl)-1H-indole-2-carboxylate

Product 1

HCID 58900292HCID 58900292, compound

Procedure

Using general procedure B, 6-trifluoromethyl-1H-indole-2-carboxylic acid methyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as white solid. MS: 368.0 ([M−H]−).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-04b7fa227e3640c692e33a9783513999
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Linked notes

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