N-bromobutanimide → 1-(Bromomethyl)-7-fluoronaphthalene

Reaction equation

[F:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][CH:8]=[C:9]2[CH3:12])=[CH:4][CH:3]=1.[Br:13]N1C(=O)CCC1=O>>[Br:13][CH2:12][C:9]1[C:10]2[C:5](=[CH:4][CH:3]=[C:2]([F:1])[CH:11]=2)[CH:6]=[CH:7][CH:8]=1

Participants

Reactant 2

HCID 67184N-bromobutanimide

HCID 685779887-Fluoro-1-methylnaphthalene

Product 1

HCID 156574201-(Bromomethyl)-7-fluoronaphthalene

Procedure

Using general procedure A (Exp. 1.3.), 7-fluoro-1-methyl-naphthalene was reacted with N-bromosuccinimide to give 1-bromomethyl-7-fluoro-naphthalene as white solid. MS: 238.1 ([M]+).

Sources & evidence

ORD record: ord-61d0870e838a43c39e5c7af1e343c15b
Source dataset: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07696240B2

Reaction notes

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