Ethyl indole-2-carboxylate → HCID 58900228, compound

HRID 642665

Reaction equation

HRID 642665 reaction equation
C([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:5])C.Cl[CH2:16][C:17]1[C:18]2[CH:25]=[CH:24][CH:23]=[CH:22][C:19]=2[S:20][CH:21]=1>>[S:20]1[CH:21]=[C:17]([CH2:16][N:7]2[C:8]3[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:14]=[C:6]2[C:4]([OH:3])=[O:5])[C:18]2[CH:25]=[CH:24][CH:23]=[CH:22][C:19]1=2

Participants

3

Reactant 2

HCID 73125Ethyl indole-2-carboxylateHCID 766803-(Chloromethyl)benzo(b)thiophene

Product 1

HCID 58900228HCID 58900228, compound

Procedure

Using general procedure B, 1H-indole-2-carboxylic acid ethyl ester was coupled with 3-chloromethyl-benzo[b]thiophene and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 306.4 ([M−H]−).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-e319522e64404625a3f038444bb31e67
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Linked notes

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