2',4'-Dichloroacetophenone → 4-(2,4-Dichlorophenyl)-1,3-thiazol-2-amine
Reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9](=O)[CH3:10].[NH2:12][C:13]([NH2:15])=[S:14]>>[NH2:15][C:13]1[S:14][CH:10]=[C:9]([C:3]2[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=2[Cl:1])[N:12]=1Participants
3
Procedure
Using 2′,4′-dichloroacetophenone and thiourea as the raw materials, the same operation as the Example 395(1) gave the title compound.
Sources & evidence
- ORD record
- ord-1c7d5cc0f332413cb2fb9865bccd3f8f
- Source dataset
- uspto-grants-2010_04
- Patent number
- US07700655B2
Reaction notes
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