4-(3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl)aniline → HCID 23069936, compound

HRID 644480

Reaction equation

HRID 644480 reaction equation
[C:1]([O:4][C:5]1[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][C:6]=1[C:7]([OH:9])=O)(=[O:3])[CH3:2].[NH2:15][C:16]1[CH:21]=[CH:20][C:19]([N:22]2[C:26]([C:27]([F:30])([F:29])[F:28])=[CH:25][C:24]([C:31]([F:34])([F:33])[F:32])=[N:23]2)=[CH:18][CH:17]=1>>[C:1]([O:4][C:5]1[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][C:6]=1[C:7]([NH:15][C:16]1[CH:17]=[CH:18][C:19]([N:22]2[C:26]([C:27]([F:28])([F:29])[F:30])=[CH:25][C:24]([C:31]([F:34])([F:33])[F:32])=[N:23]2)=[CH:20][CH:21]=1)=[O:9])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 27406684-(3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl)anilineHCID 28208132-(Acetyloxy)-5-chlorobenzoic acid

Product 1

HCID 23069936HCID 23069936, compoundYield 77.8%

Procedure

Using 2-acetoxy-5-chlorobenzoic acid and 1-(4-aminophenyl)-3,5-bis(trifluoromethyl)pyrazole as the raw materials, the same operation as the Example 24 gave the title compound.

Sources & evidence

ORD record
ord-7758e3d1fc7440c6978cf7dec38e21ef
Source dataset
uspto-grants-2010_04
Patent number
US07700655B2

Linked notes

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