Chlorotrimethylsilane → Tert-amyloxy cyclopentyl dimethoxysilane

HRID 6448

Reaction equation

HRID 6448 reaction equation
[CH:1]1([Si:6](OC)([O:9][CH3:10])[O:7][CH3:8])[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:13]([OH:18])([CH2:16][CH3:17])([CH3:15])[CH3:14].C[Si](C)(C)Cl>C[O-].[Na+]>[C:13]([O:18][Si:6]([CH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1)([O:9][CH3:10])[O:7][CH3:8])([CH2:16][CH3:17])([CH3:15])[CH3:14]

Participants

5

Reactant 3

HCID 6397ChlorotrimethylsilaneHCID 64052-Methyl-2-butanolHCID 9855701Cyclopentyltrimethoxysilane

Product 1

HCID 10988602Tert-amyloxy cyclopentyl dimethoxysilaneYield 82%

Reagents, catalysts & solvents 1

HCID 10942334Sodium MethoxideCatalyst

Procedure

In a 100 ml three-neck flask provided with a magnetic stirrer and a reflux condenser were charged 10.1 g (0.0531 mole) of cyclopentyl trimethoxysilane, 30.6 g (0.347 mole) of tert-amyl alcohol and 86.4 mg (1.6 m mole) of sodium methoxide, which were then reacted with each other in an oil bath of 105° C. for 4 hours under stirring. Then, trimethylchlorosilane was added to neutralize the alkali. Then, 10.7 g (0.0434 mole) of tert-amyloxy cyclopentyl dimethoxysilane were obtained by vacuum distillation. Its structure was confirmed as in Example 1. The yield was 82%.

Workup

  1. customIn a 100 ml three-neck flask provided with a magnetic stirrer and a reflux condenser
  2. customwere then reacted with each other in an oil bath of 105° C. for 4 hours

Sources & evidence

ORD record
ord-44523718c32f4f8db78be90afe1a804e
Source dataset
uspto-grants-1993_09
Patent number
US05248803

Linked notes

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