7-(benzyloxy)-2,3,4,5-tetrahydro-1H-3-benzazepine → HCID 59257923, compound
Reaction equation
[I:1][C:2]1[C:19]([O:20][CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:18][C:5]2[CH2:6][CH2:7][N:8](C(OC(C)(C)C)=O)[CH2:9][CH2:10][C:4]=2[CH:3]=1.C(OC1C=CC2CCNCCC=2C=1)C1C=CC=CC=1>>[I:1][C:2]1[C:19]([O:20][CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:18][C:5]2[CH2:6][CH2:7][NH:8][CH2:9][CH2:10][C:4]=2[CH:3]=1Participants
3
Procedure
Description D45 (D45) was prepared from 1,1-dimethylethyl 7-iodo-8-[(phenylmethyl)oxy]-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate (D44) using the analogous method to that described for Description 2 (D2); MS (ES+) m/e 380 [M+H]+.
Sources & evidence
- ORD record
- ord-fa0f4f78a911421cb3efa9331fd1ca74
- Source dataset
- uspto-grants-2010_04