Glyoxylic Acid → 2-Hydroxy-2-(2-hydroxyphenyl)acetic acid

Reaction equation

[C:1]([OH:5])(=[O:4])[CH:2]=[O:3].[C:6]1([OH:12])[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>>[OH:12][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[CH:2]([OH:3])[C:1]([OH:5])=[O:4]

Participants

Reactant 2

HCID 760Glyoxylic Acid

HCID 996Phenol

Product 1

HCID 1612632-Hydroxy-2-(2-hydroxyphenyl)acetic acid

Procedure

reacting glyoxylic acid with a boric acid ester of a phenol of the formula: ##STR9## under acid conditions to form a boric acid ester of a 2-hydroxymandelic acid;

Sources & evidence

ORD record: ord-bac2e5d16cf345c093dab45174ba84b2
Source dataset: uspto-grants-1993_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05248816

Reaction notes

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