2-Acetylcyclohexanone → 7-Oxooctanoic acid

Reaction equation

[C:1]([CH:4]1[CH2:9][CH2:8][CH2:7][CH2:6][C:5]1=[O:10])(=[O:3])[CH3:2].[OH-:11].[K+]>>[O:3]=[C:1]([CH3:2])[CH2:4][CH2:9][CH2:8][CH2:7][CH2:6][C:5]([OH:10])=[O:11]

Participants

Reactant 2

HCID 134002-Acetylcyclohexanone

HCID 14797Potassium Hydroxide

Product 1

HCID 264647-Oxooctanoic acid

Procedure

7-Oxooctanoic acid was prepared by treatment of 2-acetyl cyclohexanone with aqueous potassium hydroxide (S. Hunig et al; Chem Ber 91, 129-133 (1958)).

Sources & evidence

ORD record: ord-e1b1a95009504cf9bff9d61402140b73
Source dataset: uspto-grants-1993_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05248810

Reaction notes

Loading…