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2-Methylpyridine → 2-(2,2-Dichlorovinyl)-benzyl 2-(4-chlorophenyl)-isovalerate

HRID 64919
Notes
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Reaction equation

HRID 64919 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH:12]([CH3:14])[CH3:13])[C:9](Cl)=[O:10])=[CH:4][CH:3]=1.N1C=CC=CC=1C.[Cl:22][C:23]([Cl:33])=[CH:24][C:25]1[CH:32]=[CH:31][CH:30]=[CH:29][C:26]=1[CH:27]=[O:28]>C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH:12]([CH3:14])[CH3:13])[C:9]([O:28][CH2:27][C:26]2[CH:29]=[CH:30][CH:31]=[CH:32][C:25]=2[CH:24]=[C:23]([Cl:22])[Cl:33])=[O:10])=[CH:4][CH:3]=1
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

5

Reactant 3

HCID 79752-MethylpyridineHCID 41780012-(4-Chlorophenyl)-3-methylbutanoyl chlorideHCID 137131312-(2,2-Dichlorovinyl)-benzaldehyde

Product 1

HCID 137131352-(2,2-Dichlorovinyl)-benzyl 2-(4-chlorophenyl)-isovalerate

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

2.8 g (0.012 mole) of 2-(4-chlorophenyl)-isovaleryl chloride in 50 ml of absolute toluene are introduced into 1.2 g (0.013 mole) of -picoline and 3.2 g (0.015 mole) of 2-(2,2-dichlorovinyl)-benzaldehyde in a conical flask at room temperature, while stirring. After 30 minutes, the mixture is filtered under suction over silica gel, and washing is carried out with toluene.

Workup

  1. filtrationthe mixture is filtered under suction over silica gel
  2. washwashing

Sources & evidence

ORD record
ord-0f238b4ef3e5448f8833fd83cb856d4f
Source dataset
uspto-grants-1986_09
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US04611010

Reaction notes

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On this pageParticipantsProcedureWorkupSources & evidenceReaction notes