2-(4,4-Difluorobut-3-enylthio)benzthiazole → HCID 21712906, compound

HRID 650616

Reaction equation

HRID 650616 reaction equation
[F:1][C:2]([F:16])=[CH:3][CH2:4][CH2:5][S:6][C:7]1[S:8][C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[N:11]=1.[OH2:17].[OH2:18].O.O.O.O.C(OO)(=O)C1C(=CC=CC=1)C(O)=O.[Mg]>ClCCl.O>[F:16][C:2]([F:1])=[CH:3][CH2:4][CH2:5][S:6]([C:7]1[S:8][C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[N:11]=1)(=[O:18])=[O:17]

Participants

5

Reactant 2

HCID 217129092-(4,4-Difluorobut-3-enylthio)benzthiazoleHCID 86597096Magnesium monoperoxyphthalic acid hexahydrate

Product 1

HCID 21712906HCID 21712906, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolvent2×HCID 6344DichloromethaneSolvent2×

Procedure

2-(4,4-difluorobut-3-enylthio)benzthiazole (prepared by the method described in United Kingdom Patent Application GB2270689A, 8.25 g) in dichloromethane ( 15 cm3) was added to a rapidly stirred mixture of monomagnesium peroxyphthalic acid hexahydrate (25.7 g, 70-80% technical grade) in water (25 cm3). The mixture was stirred for 2 days, diluted with dichloromethane and water, the organic phase separated, washed with aqueous sodium carbonate, water and dried (magnesium sulfate). The solvent was evaporated under reduced pressure to give 2-(4,4-difluorobut-3-enylsulfonyl )benzthiazole as a colourless oil, 4.9 g.

Workup

  1. customthe organic phase separated
  2. washwashed with aqueous sodium carbonate, water
  3. dry with materialdried (magnesium sulfate)
  4. customThe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-239314f354524ad9b811097d7640845e
Source dataset
uspto-grants-2001_08
Patent number
US06274632B1

Linked notes

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