2-Methylallylamine → 7-(2-Methylallylamino)-5-methyl-1H-pyrazolo[4,3-b]pyridine

Reaction equation

Cl[C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]2[CH:9]=[N:10][NH:11][C:3]=12.[CH3:12][C:13](=[CH2:16])[CH2:14][NH2:15]>>[CH3:16][C:13](=[CH2:12])[CH2:14][NH:15][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]2[CH:9]=[N:10][NH:11][C:3]=12

Participants

Reactant 2

HCID 761412-Methylallylamine

HCID 116798717-Chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine

Product 1

HCID 137471737-(2-Methylallylamino)-5-methyl-1H-pyrazolo[4,3-b]pyridine

Procedure

The title compound was prepared from 7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine (D4) and 2-methylallylamine as a pale yellow solid, m.p. 161°-164°, by the method given in Example 1.

Sources & evidence

ORD record: ord-c84c583299a34434b70048811c378125
Source dataset: uspto-grants-1987_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04670432

Reaction notes

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