Glycol monoethyl ether → N-methylanthranilic acid nickel

HRID 652709

Reaction equation

HRID 652709 reaction equation
C([O-])(=O)C.[Ni+2:5].C([O-])(=O)C.CCOCCO.[CH3:16][NH:17][C:18]1[C:19](=[CH:23][CH:24]=[CH:25][CH:26]=1)[C:20]([OH:22])=[O:21]>O>[Ni:5].[CH3:16][NH:17][C:18]1[C:19](=[CH:23][CH:24]=[CH:25][CH:26]=1)[C:20]([OH:22])=[O:21]

Participants

5

Reactant 3

HCID 8076Glycol monoethyl etherHCID 9756Nickel AcetateHCID 67069N-Methylanthranilic acid

Product 1

HCID 86741584N-methylanthranilic acid nickelYield 138.2%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
50 °C

Procedure

23.8 g (0.1 mol) of nickel acetate was added to 500 ml of ethyl cellosolve and stirred. The mixture was heated to 50° C., and 30.2 g (0.2 mol) of N-methyl-anthranilic acid was gradually added. The mixture was subjected to reaction for 2 hours at about 130° C. under refluxing and then dispersed in 2 liters of water. After 1 hour, the dispersion was subjected to filtration and the precipitate was washed with water until neutrality. The precipitate was then dried at 90° C. to obtain about 29 g of pale blue powder.

Workup

  1. customThe mixture was subjected to reaction for 2 hours at about 130° C.
  2. temperatureunder refluxing
  3. filtrationthe dispersion was subjected to filtration
  4. washthe precipitate was washed with water until neutrality
  5. customThe precipitate was then dried at 90° C.

Sources & evidence

ORD record
ord-12a820d4ef814cc28280da2d675a0e64
Source dataset
uspto-grants-1987_06
Patent number
US04673631

Linked notes

Loading…