3-Benzyloxy-4-hydroxybenzaldehyde → 2-Chloro-3-benzyloxy-4-methoxymethoxybenzaldehyde

HRID 652804

Reaction equation

HRID 652804 reaction equation
[CH2:1]([O:8][C:9]1C=C(C=CC=1O)C=O)C1C=CC=CC=1.[Cl:18][C:19]1[C:26]([O:27][CH2:28][C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[C:25]([OH:35])[CH:24]=[CH:23][C:20]=1[CH:21]=[O:22]>>[Cl:18][C:19]1[C:26]([O:27][CH2:28][C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)=[C:25]([O:35][CH2:1][O:8][CH3:9])[CH:24]=[CH:23][C:20]=1[CH:21]=[O:22]

Participants

3

Reactant 2

HCID 110206353-Benzyloxy-4-hydroxybenzaldehydeHCID 201963712-Chloro-3-benzyloxy-4-hydroxybenzaldehyde

Product 1

HCID 201963902-Chloro-3-benzyloxy-4-methoxymethoxybenzaldehyde

Procedure

Proceeding as in example 63, but replacing for 3-benzyloxy-4-hydroxybenzaldehyde an equivalent quantity of 2-chloro-3-benzyloxy-4-hydroxybenzaldehyde obtained as described in example 85, 2-chloro-3-benzyloxy-4-methoxymethoxybenzaldehyde was obtained, m.p. 66°-67° C. (from petroleum ether, b.p. 30°-70° C.).

Workup

  1. customobtained

Sources & evidence

ORD record
ord-77f1e9e17ae84883b2875bf5c6dabf1b
Source dataset
uspto-grants-1987_06
Patent number
US04673671

Linked notes

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