Sodium Hydroxide → Acifluorfen sodium

HRID 65331

Reaction equation

HRID 65331 reaction equation
[Cl:1][C:2]1[CH:20]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:14]([O-:16])=[O:15])=[C:9]([CH:13]=1)[C:10]([OH:12])=[O:11].[OH-].[Na+:26]>CO>[Cl:1][C:2]1[CH:20]=[C:19]([C:21]([F:22])([F:23])[F:24])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:14]([O-:16])=[O:15])=[C:9]([CH:13]=1)[C:10]([O-:12])=[O:11].[Na+:26]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 44073Acifluorfen

Product 1

HCID 44072Acifluorfen sodiumYield 105.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid (1.7 g, 0.0047 mole) is dissolved in methanol (25 ml) and sodium hydroxide (4.7 ml of 1N NaOH in methanol, 0.0047 mole) is added rapidly. The solvent is then removed in vacuo to give 1.9 g of product that decomposes at 217° C.

Workup

  1. customThe solvent is then removed in vacuo

Sources & evidence

ORD record
ord-9e9b4f013e6e41fe8d4ab299c0212c3e
Source dataset
uspto-grants-1986_09
Patent number
US04613360

Linked notes

Loading…