Sodium Hydroxide → Sodium 2-chloro-3-benzyloxypropionate
Reaction equation
[Cl:1][CH:2]([CH2:6][O:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]([OH:5])=[O:4].[OH-].[Na+:16]>O>[Cl:1][CH:2]([CH2:6][O:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]([O-:5])=[O:4].[Na+:16]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
85 g of 2-chloro-3-benzyloxypropionic acid (0.396 mol) were suspended in 550 ml of water and neutralized to pH 7 with 10% sodium hydroxide. After stirring for 15 min, the resulting aqueous solution was washed with ethyl ether and evaporated to dryness under vacuum to give the desired compound.
Workup
- washthe resulting aqueous solution was washed with ethyl ether
- customevaporated to dryness under vacuum
Sources & evidence
- ORD record
- ord-ce6d7bc3a6f446ad8c73792b287efab1
- Source dataset
- uspto-grants-1992_07
- Patent number
- US05132409
Reaction notes
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