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Allyl bromide → 1-Fluoro-4-(prop-2-en-1-yloxy)benzene

HRID 654756
Notes
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Reaction equation

HRID 654756 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.[CH2:9](Br)[CH:10]=[CH2:11].[OH-].[Na+]>CC(C)=O>[CH2:11]([O:8][C:5]1[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=1)[CH:10]=[CH2:9]
ParticipantsProcedureSources & evidenceReaction notes

Participants

5

Reactant 3

HCID 7841Allyl bromideHCID 97324-FluorophenolHCID 14798Sodium Hydroxide

Product 1

HCID 6373421-Fluoro-4-(prop-2-en-1-yloxy)benzene

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

This compound was prepared from 4-fluorophenol and allyl bromide according to the process described in Example 5, stage A. The solvent used is acetone and the reaction was carried out in the presence of sodium hydroxide.

Sources & evidence

ORD record
ord-454352191bb146bd9b4c14d2b40f64ee
Source dataset
uspto-grants-1992_07
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US05134147

Reaction notes

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On this pageParticipantsProcedureSources & evidenceReaction notes