Methyl iodide → HCID 271998, compound
Reaction equation
CS[CH2:3][C:4]1[O:5][C:6]2[C:11]([C:12](=[O:14])[CH:13]=1)=[CH:10][CH:9]=[CH:8][CH:7]=2.C[I:16]>ClCCl>[I:16][CH2:3][C:4]1[O:5][C:6]2[C:11]([C:12](=[O:14])[CH:13]=1)=[CH:10][CH:9]=[CH:8][CH:7]=2Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
8 g of 2-methylthiomethyl-4-oxo-4H-chromene, 200 ml of methyl iodide and 26 ml of dichloromethane are brought to reflux with stirring for 4 days. The precipitate is filtered off, the excess solvents and reagents are evaporated off, the residue is taken up with ethyl ether and the organic phase is washed with sodium thiosulfate solution, dried and evaporated.
Workup
- temperatureto reflux
- filtrationThe precipitate is filtered off
- customthe excess solvents and reagents are evaporated off
- washthe organic phase is washed with sodium thiosulfate solution
- customdried
- customevaporated
Sources & evidence
- ORD record
- ord-c1e1cedb3d38419a9113e8e0273f4061
- Source dataset
- uspto-grants-1992_07
- Patent number
- US05134147
Reaction notes
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