HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,5-Trimethoxybenzaldehyde → Tetrahydro-3,5-bis[(3,4,5-trimethoxyphenyl)methylene]-4H-pyran-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,5-Trimethoxybenzaldehyde | HCID 6858 | — |
| Reactant | Tetrahydro-4H-pyran-4-one | HCID 121599 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Tetrahydro-3,5-bis[(3,4,5-trimethoxyphenyl)methylene]-4H-pyran-4-one | HCID 2740872 | — |
Reaction Steps
A solution of 6.0 g (0.06 mole) of tetrahydro-4H-pyran-4-one and 25 g (0.127 mole) of 3,4,5-trimethoxybenzaldehyde in 75 ml of EtOH and 10 ml of concentrated HCl is stirred and heated at reflux for 3 hours. The product gradually precipitates from the cooled solution. The yield of yellow crystals is 12.0 g (44%), m.p. 187°-189°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04128648 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-48d5a20802204161ac721fb022201aab |
| Source note | uspto-grants-1978_12 |