Butyn-2-one → 2-Acetyl-6-methylpyrazolo[1,5-c]quinazolin-5(6H)-one

HRID 65685

Reaction equation

HRID 65685 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[N+:11]=[N-:12])[C:3]1=[O:13].[CH3:14][C:15](=[O:18])[C:16]#[CH:17]>C1C=CC=CC=1>[C:15]([C:16]1[CH:17]=[C:4]2[N:11]([C:3](=[O:13])[N:2]([CH3:1])[C:10]3[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=32)[N:12]=1)(=[O:18])[CH3:14]

Participants

4

Reactant 2

HCID 15018Butyn-2-oneHCID 178481574HCID 178481574, compound

Product 1

HCID 129616092-Acetyl-6-methylpyrazolo[1,5-c]quinazolin-5(6H)-one

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

To a solution of 5.0 g (0.0288 mole) of 1-methyl-3-diazooxindole in 200 ml of benzene there is added 2.38 g (0.035 mole) of 3-butyn-2-one and the solution refluxed overnight.

Workup

  1. temperaturethe solution refluxed overnight

Sources & evidence

ORD record
ord-76d7d52960d34b70b257f35b5fe228d0
Source dataset
uspto-grants-1978_12
Patent number
US04128644

Linked notes

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