HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethyl isothiocyanate → N-[2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl]-N'-(2-methoxyethyl)thiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethyl isothiocyanate | HCID 123475 | — |
| Reactant | 5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine | HCID 162203 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N-[2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl]-N'-(2-methoxyethyl)thiourea | HCID 23452142 | — |
Reaction Steps
1-(Isothiocyanato)-2-methoxyethane (1.17 g) and 2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethanamine (2.14 g) in acetonitrile were stood overnight. Solvent was removed and the residual oil chromatographed (silica/methanol) to give N-[2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl]-N'-(2-methoxyethyl)thiourea as a pale oil Rf 0.45. Analysis Found: C, 50.64; H, 7.51; N, 12.58. C14H25N3O2S2 requires: C, 50.75; H, 7.55; N, 12.69%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04128658 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-174fa428c3f94ac1a7b6326f553fcc8d |
| Source note | uspto-grants-1978_12 |