Dichloromethane → Terephthaloyl chloride

Participants

Reaction Steps

Following the general procedure of Example 9, but using more concentrated reaction media, a slurry of 8.22 parts terephthalic acid in 50 parts dry dichloromethane was added to a stirred mixture of 8.85 parts pyridine and 10.46 parts phosgene in 80 parts dry dichloromethane at 24° to 30° C. The ratio of equivalents of pyridine base/COOH acid group was 1.13. After carrying out the reaction and esterifying the resulting diacid chloride by the procedure as described in Example 1, a quantitative yield of dimethyl terephthalate was formed corresponding to a quantitative yield of terephthaloyl chloride formed initially in the reaction.

Provenance & Evidence