HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-2-thiopseudourea sulfate → Guanidine Sulfate (1:1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-2-thiopseudourea sulfate | HCID 75270 | — |
| Reactant | HCID 178433288 | HCID 178433288 | — |
| Solvent | Water | HCID 962 | — |
| Product | Guanidine Sulfate (1:1) | HCID 499987 | 103.1% |
Reaction Steps
A solution of 4-methyl-5-((2-aminoethyl)thiomethyl)imidazole (19.0 g.) and S-methylisothiourea sulphate (15.1 g.) in water (100 ml.) was heated under reflux for 3 hours. Concentration, acidification with sulphuric acid and dilution with ethanol afforded 2-[(4-methyl-5-imidazolyl)methylthio)ethyl]guanidine sulphate (13.0 g.) m.p. 230°-235° (from aqueous methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04129657 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-d142530121634bff9dac22d3af7bde46 |
| Source note | uspto-grants-1978_12 |