Ethanol → Sodium 8-aminonaphthalene-1,3,5-trisulfonate

HRID 66027

Reaction equation

HRID 66027 reaction equation
[NH2:1][C:2]1[C:11]2[C:10]([S:12]([OH:15])(=[O:14])=[O:13])=[CH:9][C:8]([S:16]([OH:19])(=[O:18])=[O:17])=[CH:7][C:6]=2[C:5]([S:20]([OH:23])(=[O:22])=[O:21])=[CH:4][CH:3]=1.C(O)C.[OH-].[Na+:28]>O>[Na+:28].[Na+:28].[Na+:28].[NH2:1][C:2]1[C:11]2[C:10]([S:12]([O-:15])(=[O:14])=[O:13])=[CH:9][C:8]([S:16]([O-:19])(=[O:17])=[O:18])=[CH:7][C:6]=2[C:5]([S:20]([O-:23])(=[O:22])=[O:21])=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 873558-Aminonaphthalene-1,3,5-trisulfonic acid

Product 1

HCID 10343683Sodium 8-aminonaphthalene-1,3,5-trisulfonate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a warm solution of 23.8 g of 80.5% 8-amino-1,3,5-naphthalenetrisulfonic acid in 25 ml of water and 25 ml of 5N sodium hydroxide are slowly added 125 ml of absolute ethyl alcohol with vigorous stirring. The mixture is cooled to room temperature, is filtered and washed with 50 ml of 80% aqueous ethyl alcohol, then ethyl alcohol and ether. The material is dried overnight at 110° C. to give 21.0 g of 8-amino-1,3,5-naphthalenetrisulfonic acid trisodium salt as a powder.

Workup

  1. filtrationis filtered
  2. washwashed with 50 ml of 80% aqueous ethyl alcohol
  3. customThe material is dried overnight at 110° C.

Sources & evidence

ORD record
ord-7dfe41afc4d44a90a08d7939ac17b363
Source dataset
uspto-grants-1978_12
Patent number
US04129590

Linked notes

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