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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 66053Generated: October 26, 2026

Sodium Hydroxide → Ampicillin Sodium

https://huagongshe.com/reaction/66053

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantAmpicillin TrihydrateHCID 23565—
SolventWaterHCID 962—
ProductAmpicillin SodiumHCID 23663979—

Reaction Steps

A suspension of 24.18 gm (60 millimols) of ampicillin trihydrate in 140 ml of water was admixed with 55.2 ml of an aqueous 1N sodium hydroxide solution (8% less than equimolar amount of NaOH) in the manner and under the conditions described in Example 1, and the sodium ampicillin was isolated in exactly the same manner as in Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04130558
Source datasetuspto-grants-1978_12
ORD IDord-177c8f38f14b4e4d99132f91365c0976
Source noteuspto-grants-1978_12