tert-Butyl N-(4-hydroxybutyl)carbamate → [4-(3-Hydroxy-2-methylsulfanylphenoxy)-butyl]-carbamic Acid Tert-butyl Ester

HRID 660626Notes

Reaction equation

HRID 660626 reaction equation
[CH3:1][S:2][C:3]1[C:8]([OH:9])=[CH:7][CH:6]=[CH:5][C:4]=1[OH:10].[C:11]([NH:18][CH2:19][CH2:20][CH2:21][CH2:22]O)([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12]>>[C:14]([O:13][C:11](=[O:12])[NH:18][CH2:19][CH2:20][CH2:21][CH2:22][O:10][C:4]1[CH:5]=[CH:6][CH:7]=[C:8]([OH:9])[C:3]=1[S:2][CH3:1])([CH3:17])([CH3:16])[CH3:15]

Participants

3

Reactant 2

HCID 545141tert-Butyl N-(4-hydroxybutyl)carbamateHCID 688384622-Methylsulfanylbenzene-1,3-diol

Product 1

HCID 68839720[4-(3-Hydroxy-2-methylsulfanylphenoxy)-butyl]-carbamic Acid Tert-butyl Ester

Procedure

The title compound is prepared from 2-methylsulfanylbenzene-1,3-diol and 4-(Boc-amino)-1-butanol analogous to Example 1101 step A.

Sources & evidence

ORD record
ord-92e237fe5e2e4fa38539ec9e5f86e516
Source dataset
uspto-grants-2011_12
Patent number
US08084448B2

Reaction notes

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