3,3-Dimethyl-1-butene → 5-[4-(3,3-Dimethylbutyl)-2-hydroxyphenyl]-1,1-dioxo-1,2,5-thiadiazolidin-3-one
Reaction equation
C([O:8][C:9]1[CH:14]=[C:13](I)[CH:12]=[CH:11][C:10]=1[N:16]1[S:20](=[O:22])(=[O:21])[NH:19][C:18](=[O:23])[CH2:17]1)C1C=CC=CC=1.[CH3:24][C:25]([CH3:29])([CH3:28])[CH:26]=[CH2:27]>>[CH3:24][C:25]([CH3:29])([CH3:28])[CH2:26][CH2:27][C:13]1[CH:12]=[CH:11][C:10]([N:16]2[S:20](=[O:21])(=[O:22])[NH:19][C:18](=[O:23])[CH2:17]2)=[C:9]([OH:8])[CH:14]=1Participants
3
Procedure
The title compound is prepared from 5-(2-benzyloxy-4-iodophenyl)-1,1-dioxo-1,2,5-thiadiazolidin-3-one and 3,3-dimethylbut-1-ene analogous to Example 300: (M−1)−=311; HPLC retention time=1.20 min (method A).
Sources & evidence
- ORD record
- ord-bcfcc77986924cff964cdc6190acb463
- Source dataset
- uspto-grants-2011_12