HCID 67499044, compound → HCID 67499337, compound

Reaction equation

[F:1][C:2]1([C:12]2[S:13][CH:14]=[CH:15][N:16]=2)[CH2:11][CH2:10][C:5]2(OCC[O:6]2)[CH2:4][CH2:3]1.ClC1C(C2(F)CCC3(OCCO3)CC2)=NC=CC=1>>[F:1][C:2]1([C:12]2[S:13][CH:14]=[CH:15][N:16]=2)[CH2:3][CH2:4][C:5](=[O:6])[CH2:10][CH2:11]1

Participants

Reactant 2

HCID 67499044HCID 67499044, compound

HCID 67499172HCID 67499172, compound

Product 1

HCID 67499337HCID 67499337, compound

Procedure

The title compound was prepared using the procedure as described in Example 1C, except for substituting the product of Example 20B for the product of Example 1B. 1H NMR (300 MHz, DMSO-d6) δ ppm 7.82-7.95 (m, 2 H), 2.61-2.72 (m, 6 H), 2.24-2.42 (m, 2 H). MS (DCI) m/e 200 (M+H)+.

Sources & evidence

ORD record: ord-04c3b1848ef0461499d53fb207c48ce5
Source dataset: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08084616B2

Reaction notes

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