Dichloromethane → 1-(5-Methoxy-pyrimidin-2-yl)-4,4-dimethyl-piperidine-2,6-dione

Reaction equation

[CH3:10][C:11]1([CH3:19])[CH2:12][C:13](=[O:14])[O:15][C:16](=[O:18])[CH2:17]1.[CH3:1][O:2][c:3]1[cH:4][n:5][c:6]([NH2:9])[n:7][cH:8]1.[Cl:20][CH2:21][Cl:22]>>[CH3:1][O:2][c:3]1[cH:4][n:5][c:6]([N:9]2[C:13](=[O:14])[CH2:12][C:11]([CH3:10])([CH3:19])[CH2:17][C:16]2=[O:15])[n:7][cH:8]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 778133,3-Dimethylglutaric anhydride

HCID 23052442-Amino-5-methoxypyrimidine

Product 1

HCID 220478711-(5-Methoxy-pyrimidin-2-yl)-4,4-dimethyl-piperidine-2,6-dione

Sources & evidence

ORD record: ord-9c41d0d7ca87422aa5527f5a60af69fa
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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