2-Bromo-4-ethylpyridine → N-(4-chloro-3-(4-ethylpyridin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide

HRID 664920

Reaction equation

HRID 664920 reaction equation
[CH2:31]([CH3:32])[c:33]1[cH:34][c:35]([Br:39])[n:36][cH:37][cH:38]1.[Cl:1][c:2]1[c:3]([B:22]2[O:23][C:24]([CH3:25])([CH3:26])[C:27]([CH3:28])([CH3:29])[O:30]2)[cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([CH3:20])[n:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)=[O:21])[cH:6][cH:7]1>>[Cl:1][c:2]1[c:3](-[c:35]2[cH:34][c:33]([CH2:31][CH3:32])[cH:38][cH:37][n:36]2)[cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([CH3:20])[n:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)=[O:21])[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 41142482-Bromo-4-ethylpyridineHCID 66896658N-(4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide

Product 1

HCID 58614779N-(4-chloro-3-(4-ethylpyridin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide

Sources & evidence

ORD record
ord-ab3c4855aa4042e589ab25d2063e0afb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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