2-((Tert-butyldimethylsilyl)oxy)acetaldehyde → 3-[2-(Tert-butyl-dimethyl-silanyloxy)-ethylamino]-5-(3,5-dicyano-2,6-dimethyl-1,4-dihydro-pyridin-4-yl)-indazole-1-carboxylic acid tert-butyl ester

HRID 665191

Reaction equation

HRID 665191 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[n:9][c:10]([NH2:29])[c:11]2[cH:12][c:13]([CH:17]3[C:18]([C:27]#[N:28])=[C:19]([CH3:26])[NH:20][C:21]([CH3:25])=[C:22]3[C:23]#[N:24])[cH:14][cH:15][c:16]12.[C:30]([CH3:31])([CH3:32])([CH3:33])[Si:34]([O:35][CH2:36][CH:37]=[O:38])([CH3:39])[CH3:40]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[n:9][c:10]([NH:29][CH2:37][CH2:36][O:35][Si:34]([C:30]([CH3:31])([CH3:32])[CH3:33])([CH3:39])[CH3:40])[c:11]2[cH:12][c:13]([CH:17]3[C:18]([C:27]#[N:28])=[C:19]([CH3:26])[NH:20][C:21]([CH3:25])=[C:22]3[C:23]#[N:24])[cH:14][cH:15][c:16]12

Participants

3

Reactant 2

HCID 41877882-((Tert-butyldimethylsilyl)oxy)acetaldehydeHCID 24959832tert-Butyl 3-amino-5-(3,5-dicyano-2,6-dimethyl-1,4-dihydropyridin-4-yl)-1H-indazole-1-carboxylate

Product 1

HCID 690441213-[2-(Tert-butyl-dimethyl-silanyloxy)-ethylamino]-5-(3,5-dicyano-2,6-dimethyl-1,4-dihydro-pyridin-4-yl)-indazole-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-9b4cf37f402742f0b48419e8e52f1bf1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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