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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 66599Generated: October 26, 2026

2-Chloro-6-hydroxybenzaldehyde → 5-Chloro-1-benzofuran-2-carboxylic acid

https://huagongshe.com/reaction/66599

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-hydroxybenzaldehydeHCID 528393—
Reactant5-Fluoro-1-benzofuran-2-carboxylic acidHCID 10986872—
Reactant6-Chloro-1-benzofuran-2-carboxylic acidHCID 13748704—
Product5-Chloro-1-benzofuran-2-carboxylic acidHCID 937838—

Reaction Steps

By the same procedure, 5-fluorosalicyaldehyde and 6-chlorosalicylaldehyde are converted, respectively, to 5-fluorobenzo[b]furan-2-carboxylic acid and 6-chlorobenzo[b]furan-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04342771
Source datasetuspto-grants-1982_08
ORD IDord-9d6d6bcbf28a46838f85a3693706725c
Source noteuspto-grants-1982_08