Diethylaminopropyl chloride, hydrochloride → 1-[2-Chloro-4-(3-diethylaminopropoxy)phenyl]-1-butanone

HRID 66605Notes

Reaction equation

HRID 66605 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([O:8][CH2:9][CH2:10]N(CC)CC)[CH:5]=[CH:4][C:3]=1[C:16](=[O:20])[CH2:17][CH2:18][CH3:19].Cl.[CH2:22]([N:24]([CH2:29]C)[CH2:25][CH2:26]CCl)[CH3:23]>>[Cl:1][C:2]1[CH:7]=[C:6]([O:8][CH2:9][CH2:10][CH2:29][N:24]([CH2:25][CH3:26])[CH2:22][CH3:23])[CH:5]=[CH:4][C:3]=1[C:16](=[O:20])[CH2:17][CH2:18][CH3:19]

Participants

3

Reactant 2

HCID 145749Diethylaminopropyl chloride, hydrochlorideHCID 130523711-[2-Chloro-4-(2-diethylaminoethoxy)phenyl]-1-butanone

Product 1

HCID 204971651-[2-Chloro-4-(3-diethylaminopropoxy)phenyl]-1-butanone

Procedure

This compound is prepared by essentially the same procedure as described in Example 1 Step A except that the 2-diethylaminoethyl chloride hydrochloride of Example 1 Step A is replaced by an equimolecular quantity of 3-diethylaminopropyl chloride hydrochloride. The product is obtained as a colorless oil upon distillation in vacuo (0.2 mm.).

Workup

  1. customThis compound is prepared by essentially the same procedure
  2. customThe product is obtained as a colorless oil upon distillation in vacuo (0.2 mm.)

Sources & evidence

ORD record
ord-21363d6d9f5b4394848a22a607524986
Source dataset
uspto-grants-1982_08
Patent number
US04342782

Reaction notes

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