1-[2-Chloro-4-(2-diethylaminoethoxy)phenyl]-2-methylene-1-butanone → 1-[2-Chloro-4-(3-dimethylamino-2-methylpropoxy)phenyl]-2-methylene-1-butanone
Reaction equation
Cl[C:2]1C=C(OCCN(CC)CC)C=CC=1C(=O)C(=C)CC.[Cl:22][C:23]1[CH:28]=[C:27]([O:29][CH2:30][CH:31]([CH3:36])[CH2:32][N:33]([CH3:35])[CH3:34])[CH:26]=[CH:25][C:24]=1[C:37](=[O:41])[CH2:38][CH2:39][CH3:40]>>[Cl:22][C:23]1[CH:28]=[C:27]([O:29][CH2:30][CH:31]([CH3:36])[CH2:32][N:33]([CH3:34])[CH3:35])[CH:26]=[CH:25][C:24]=1[C:37](=[O:41])[C:38](=[CH2:2])[CH2:39][CH3:40]Participants
3
Procedure
This compound is prepared by essentially the same procedure as described in Example 1 Step B except that the 2-chloro-4-(2-diethylaminoethoxy)butyrophenone of Example 1 Step B is replaced by an equimolecular quantity of 1-[2-chloro-4-(3-dimethylamino-2-methylpropoxy)phenyl]-1-butanone. The product is obtained as a yellow oil upon distillation in vacuo (0.3 mm.).
Workup
- custom